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The ultrastructural localization of glycosaminoglycans GAGs in the developing human outflow apparatus was investigated. The aqueous outflow system from human eyes at 26th and 36th fetal week and 2 years of age was stained with ruthenium red to identify GAGs with the transmission electron microscope. Luminal surface of the inner wall of the Schlemm's canal, basal lamina of the endothelial cells, basal lamina-like material, amorphous substances and collagen fibrils in juxta-canalicular tissue were associated with ruthenium red-stainable material. The basal lamina of the endothelial cells of Schlemm's canal was stained less obviously in 2-year-old trabecular tissue.
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[Demonstration of glycosaminoglycans (GAGs) in fetal human trabecular tissue].

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